Genetic testing for BRCA1 and BRCA2 Mutations

BRCAaccuTest ™ and BRCAaccuTest ™ PLUS are a reagent kit for producing libraries to analyze BRCA1 and BRCA2 genes using the next generation sequencing (NGS) method, which analyzes genomic DNA derived from blood or FFPE tissue.

  • For patients with breast and ovarian cancer
  • For patients with HBOC (hereditary breast and ovarian cancer syndrome)
  • For family history or age of incidence of breast cancer

Specification Of BRCAaccuTest ™ PLUS

Certification: CE-IVD

Target disease:

  • Breast / ovarian cancer,
  • HBOC (hereditary breast and ovarian cancer syndrome)

Target enrichment method: Amplicon-based method


  • test 12 (6 + 6)
    (1 test for each control DNA)
  • 24 tests
    (1 test for control DNA)

Sample: Blood, FFPE tissue, tissue biopsy

Amount of input DNA: 10-30 ng

Target gene: BRCA1 / BRCA2

Target region:

22.4 kb (all protein-coding regions, splice regions, selected promoter, UTR, intronic regions)

Amplicon: 160 (2 pools)

Hands-on work: > 5 hours

Variant type:  SNV, In, Del, Dup, CNV *

NGS platform and reagent kit: Illumina MiSeq, MiSeq Dx / MiSeq Reagent Nano, Micro kit, v2, 300 cycles

Sample Yield: Germline (11) / Somatic (5) Germline (23)

Analysis Solution: NGeneAnalySys ™ (CE)

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