BRCAaccuTest PLUS
Genetic testing for BRCA1 and BRCA2 Mutations
BRCAaccuTest ™ and BRCAaccuTest ™ PLUS are a reagent kit for producing libraries to analyze BRCA1 and BRCA2 genes using the next generation sequencing (NGS) method, which analyzes genomic DNA derived from blood or FFPE tissue.
- For patients with breast and ovarian cancer
- For patients with HBOC (hereditary breast and ovarian cancer syndrome)
- For family history or age of incidence of breast cancer
Specification Of BRCAaccuTest ™ PLUS
Certification: CE-IVD
Target disease:
- Breast / ovarian cancer,
- HBOC (hereditary breast and ovarian cancer syndrome)
Target enrichment method: Amplicon-based method
Quantity
- test 12 (6 + 6)
(1 test for each control DNA) - 24 tests
(1 test for control DNA)
Sample: Blood, FFPE tissue, tissue biopsy
Amount of input DNA: 10-30 ng
Target gene: BRCA1 / BRCA2
Target region:
22.4 kb (all protein-coding regions, splice regions, selected promoter, UTR, intronic regions)
Amplicon: 160 (2 pools)
Hands-on work: > 5 hours
Variant type: SNV, In, Del, Dup, CNV *
NGS platform and reagent kit: Illumina MiSeq, MiSeq Dx / MiSeq Reagent Nano, Micro kit, v2, 300 cycles
Sample Yield: Germline (11) / Somatic (5) Germline (23)
Analysis Solution: NGeneAnalySys ™ (CE)
